QTRT1 Back

queuine tRNA-ribosyltransferase 1 (tRNA-guanine transglycosylase)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of QTRT1

This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of this gene is located on the long arm of chromosome X.

Community Annotation of QTRT1 Add / Edit QTRT1: Annotations

No community annotations yet for QTRT1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

QTRT1 is highly significantly mutated in
(none)
QTRT1 is significantly mutated in
(none)
QTRT1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for QTRT1