PTH2R Back

parathyroid hormone 2 receptor

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PTH2R
The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants.

Community Annotation of PTH2R Add / Edit PTH2R: Annotations

No community annotations yet for PTH2R.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PTH2R is highly significantly mutated in
(none)
PTH2R is significantly mutated in
(none)
PTH2R is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PTH2R