PTGR2 Back

prostaglandin reductase 2

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PTGR2

This gene encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants.

Community Annotation of PTGR2 Add / Edit PTGR2: Annotations

No community annotations yet for PTGR2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PTGR2 is highly significantly mutated in
(none)
PTGR2 is significantly mutated in
(none)
PTGR2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PTGR2