PTGIR Back

prostaglandin I2 (prostacyclin) receptor (IP)

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NCBI Description of PTGIR
The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.

Community Annotation of PTGIR Add / Edit PTGIR: Annotations

No community annotations yet for PTGIR.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PTGIR is highly significantly mutated in
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PTGIR is significantly mutated in
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PTGIR is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PTGIR