PTGES2 Back

prostaglandin E synthase 2

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NCBI Description of PTGES2
The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PTGES2 is highly significantly mutated in
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PTGES2 is significantly mutated in
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PTGES2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PTGES2