PTCRA Back

pre T-cell antigen receptor alpha

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NCBI Description of PTCRA

The protein encoded by this gene is a single-pass type I membrane protein that is found in immmature but not mature T-cells. Along with TCRB and CD3 complex, the encoded protein forms the pre-T-cell receptor complex, which regulates early T-cell development. Four transcript variants encoding different isoforms have been found for this gene.

Community Annotation of PTCRA Add / Edit PTCRA: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PTCRA is highly significantly mutated in
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PTCRA is significantly mutated in
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PTCRA is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PTCRA