PSMD14 Back

proteasome (prosome, macropain) 26S subunit, non-ATPase, 14

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NCBI Description of PSMD14
This gene encodes a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes the degradation of ubiquitinated intracellular proteins. The encoded protein is a component of the 19S regulatory cap complex of the 26S proteasome and mediates substrate deubiquitination. A pseudogene of this gene is also located on the long arm of chromosome 2.

Community Annotation of PSMD14 Add / Edit PSMD14: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PSMD14 is highly significantly mutated in
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PSMD14 is significantly mutated in
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PSMD14 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PSMD14