PSMD10 Back

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

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NCBI Description of PSMD10
This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.

Community Annotation of PSMD10 Add / Edit PSMD10: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PSMD10 is highly significantly mutated in
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PSMD10 is significantly mutated in
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PSMD10 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PSMD10