PSD Back

pleckstrin and Sec7 domain containing

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NCBI Description of PSD

This gene encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PSD is highly significantly mutated in
(none)
PSD is significantly mutated in
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PSD is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PSD