PRSS2 Back

protease, serine, 2 (trypsin 2)

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NCBI Description of PRSS2
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PRSS2 is highly significantly mutated in
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PRSS2 is significantly mutated in
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PRSS2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PRSS2