PRR5-ARHGAP8 Back

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NCBI Description of PRR5-ARHGAP8
The PRR5-ARHGAP8 mRNA is an infrequent but naturally occurring read-through transcript of the neighboring proline rich 5, renal (PRR5) and Rho GTPase activating protein 8 (ARHGAP8) genes. The resulting fusion protein contains sequence identity with each individual gene product, and it includes domains characteristic of a RhoGAP protein. The significance of this read-through transcript and the function of its protein product have not yet been determined. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Community Annotation of PRR5-ARHGAP8 Add / Edit PRR5-ARHGAP8: Annotations

No community annotations yet for PRR5-ARHGAP8.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PRR5-ARHGAP8 is highly significantly mutated in
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PRR5-ARHGAP8 is significantly mutated in
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PRR5-ARHGAP8 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PRR5-ARHGAP8