PRPH Back

peripherin

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NCBI Description of PRPH
This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis.

Community Annotation of PRPH Add / Edit PRPH: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PRPH is highly significantly mutated in
(none)
PRPH is significantly mutated in
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PRPH is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PRPH