PRPF6 Back

PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)

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NCBI Description of PRPF6
The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing.

Community Annotation of PRPF6 Add / Edit PRPF6: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PRPF6 is highly significantly mutated in
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PRPF6 is significantly mutated in
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PRPF6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PRPF6