PRP4 pre-mRNA processing factor 4 homolog B (yeast)

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NCBI Description of PRPF4B

Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs).

Community Annotation of PRPF4B Add / Edit PRPF4B: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PRPF4B is highly significantly mutated in
PRPF4B is significantly mutated in
PRPF4B is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PRPF4B