NCBI Description of PROP1
|This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin, and thyroid-stimulating hormone.|
Community Annotation of PROP1 Add / Edit PROP1: Annotations
No community annotations yet for PROP1.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.