PRMT8 Back

protein arginine methyltransferase 8

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NCBI Description of PRMT8

Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 [PubMed 16051612]).[supplied by OMIM, Mar 2008].

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PRMT8 is highly significantly mutated in
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PRMT8 is significantly mutated in
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PRMT8 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PRMT8