PRM2 Back

protamine 2

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NCBI Description of PRM2

Protamines are the major DNA-binding proteins in the nucleus of sperm, and package the DNA in a volume less than 5% of a somatic cell nucleus (summarized by Cho et al., 2001 [PubMed 11326282]). See PRM1 (MIM 182880).[supplied by OMIM, Jul 2010].

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PRM2 is highly significantly mutated in
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PRM2 is significantly mutated in
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PRM2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PRM2