PRKD1 Back

protein kinase D1

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NCBI Description of PRKD1
PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al., 2009 [PubMed 19329994]).[supplied by OMIM, Nov 2010].

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PRKD1 is highly significantly mutated in
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PRKD1 is significantly mutated in
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PRKD1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PRKD1