PREP Back

prolyl endopeptidase

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NCBI Description of PREP
The protein encoded by this gene is a cytosolic prolyl endopeptidase that cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. Prolyl endopeptidases have been reported to be involved in the maturation and degradation of peptide hormones and neuropeptides. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Community Annotation of PREP Add / Edit PREP: Annotations

No community annotations yet for PREP.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PREP is highly significantly mutated in
(none)
PREP is significantly mutated in
(none)
PREP is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PREP