PRDX6 Back

peroxiredoxin 6

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NCBI Description of PRDX6
The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PRDX6 is highly significantly mutated in
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PRDX6 is significantly mutated in
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PRDX6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PRDX6