PRDX1 Back

peroxiredoxin 1

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NCBI Description of PRDX1

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene.

Community Annotation of PRDX1 Add / Edit PRDX1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PRDX1 is highly significantly mutated in
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PRDX1 is significantly mutated in
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PRDX1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PRDX1