PPRC1 Back

peroxisome proliferator-activated receptor gamma, coactivator-related 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PPRC1

The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPARGC1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals.

Community Annotation of PPRC1 Add / Edit PPRC1: Annotations

No community annotations yet for PPRC1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PPRC1 is highly significantly mutated in
PPRC1 is significantly mutated in
PPRC1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PPRC1