PPP6C Back

protein phosphatase 6, catalytic subunit

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NCBI Description of PPP6C

This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. Splice variants encoding different protein isoforms exist. The pseudogene of this gene is located on chromosome X.

Community Annotation of PPP6C Add / Edit PPP6C: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PPP6C is highly significantly mutated in
PPP6C is significantly mutated in
11 patients (9%)
PPP6C is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PPP6C