PPP3CC Back

protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform

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NCBI Description of PPP3CC

Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene.

Community Annotation of PPP3CC Add / Edit PPP3CC: Annotations

No community annotations yet for PPP3CC.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PPP3CC is highly significantly mutated in
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PPP3CC is significantly mutated in
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PPP3CC is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PPP3CC