PPP1R3F Back

protein phosphatase 1, regulatory (inhibitor) subunit 3F

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NCBI Description of PPP1R3F

This gene encodes a protein that has been identified as one of several type-1 protein phosphatase (PP1) regulatory subunits. One or two of these subunits, together with the well-conserved catalytic subunit, can form the PP1 holoenzyme, where the regulatory subunit functions to regulate substrate specificity and/or targeting to a particular cellular compartment. Alternative splicing results in multiple transcript variants.

Community Annotation of PPP1R3F Add / Edit PPP1R3F: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PPP1R3F is highly significantly mutated in
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PPP1R3F is significantly mutated in
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PPP1R3F is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PPP1R3F