PPP1R3C Back

protein phosphatase 1, regulatory (inhibitor) subunit 3C

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NCBI Description of PPP1R3C

This gene encodes a regulatory subunit of protein phosphatase-1 (PP1). PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities: neuronal, muscular, RNA splicing, protein synthesis, cell death, and glycogen metabolism, to name just a few. By interacting with different regulatory subunits, PP1 is directed to different parts of the cell, to different substrates, or to respond to extracellular signals.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PPP1R3C is highly significantly mutated in
PPP1R3C is significantly mutated in
PPP1R3C is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PPP1R3C