PPP1R3B Back

protein phosphatase 1, regulatory (inhibitor) subunit 3B

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of PPP1R3B
This gene encodes the catalytic subunit of the serine/theonine phosphatase, protein phosphatase-1. The encoded protein is expressed in liver and skeletal muscle tissue and may be involved in regulating glycogen synthesis in these tissues. This gene may be a involved in type 2 diabetes and maturity-onset diabetes of the young. Alternate splicing results in multiple transcript variants that encode the same protein.

Community Annotation of PPP1R3B Add / Edit PPP1R3B: Annotations

No community annotations yet for PPP1R3B.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PPP1R3B is highly significantly mutated in
(none)
PPP1R3B is significantly mutated in
(none)
PPP1R3B is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PPP1R3B