PPP1R3A Back

protein phosphatase 1, regulatory (inhibitor) subunit 3A

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NCBI Description of PPP1R3A
The glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. This gene encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen-bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase kinase.

Community Annotation of PPP1R3A Add / Edit PPP1R3A: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PPP1R3A is highly significantly mutated in
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PPP1R3A is significantly mutated in
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PPP1R3A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PPP1R3A