PPP1R1C Back

protein phosphatase 1, regulatory (inhibitor) subunit 1C

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NCBI Description of PPP1R1C
Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al., 2008 [PubMed 18310074]).[supplied by OMIM, Feb 2010].

Community Annotation of PPP1R1C Add / Edit PPP1R1C: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PPP1R1C is highly significantly mutated in
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PPP1R1C is significantly mutated in
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PPP1R1C is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PPP1R1C