PPP1R15A Back

protein phosphatase 1, regulatory (inhibitor) subunit 15A

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NCBI Description of PPP1R15A
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.

Community Annotation of PPP1R15A Add / Edit PPP1R15A: Annotations

No community annotations yet for PPP1R15A.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PPP1R15A is highly significantly mutated in
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PPP1R15A is significantly mutated in
(none)
PPP1R15A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PPP1R15A