PPP1R14D Back

protein phosphatase 1, regulatory (inhibitor) subunit 14D

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NCBI Description of PPP1R14D

Protein phosphatase-1 (PP1; see MIM 176875) is a major cellular phosphatase that reverses serine/threonine protein phosphorylation. PPP1R14D is a PP1 inhibitor that itself is regulated by phosphorylation (Liu et al., 2004 [PubMed 12974676]).[supplied by OMIM, Feb 2010].

Community Annotation of PPP1R14D Add / Edit PPP1R14D: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PPP1R14D is highly significantly mutated in
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PPP1R14D is significantly mutated in
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PPP1R14D is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PPP1R14D