PPP1R10 Back

protein phosphatase 1, regulatory (inhibitor) subunit 10

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NCBI Description of PPP1R10

This gene encodes a protein phosphatase 1 binding protein. The encoded protein plays a role in many cellular processes including cell cycle progression, DNA repair and apoptosis by regulating the activity of protein phosphatase 1. This gene lies within the major histocompatibility complex class I region on chromosome 6, and alternatively spliced transcript variants have been observed for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PPP1R10 is highly significantly mutated in
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PPP1R10 is significantly mutated in
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PPP1R10 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for PPP1R10