PPP1CC Back

protein phosphatase 1, catalytic subunit, gamma isoform

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NCBI Description of PPP1CC
The protein encoded by this gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three closely related isoforms, alpha, beta/delta and gamma, which have distinct localization patterns. This gene encodes the gamma isozyme. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PPP1CC is highly significantly mutated in
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PPP1CC is significantly mutated in
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PPP1CC is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PPP1CC