PPIP5K1 Back

diphosphoinositol pentakisphosphate kinase 1

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NCBI Description of PPIP5K1
This gene encodes a dual functional inositol kinase. The encoded enzyme converts inositol hexakisphosphate to diphosphoinositol pentakisphosphate and diphosphoinositol pentakisphosphate to bis-diphosphoinositol tetrakisphosphate. This protein may be important for intracellular signaling pathways. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 15.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PPIP5K1 is highly significantly mutated in
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PPIP5K1 is significantly mutated in
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PPIP5K1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PPIP5K1