PPIL2 Back

peptidylprolyl isomerase (cyclophilin)-like 2

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NCBI Description of PPIL2
This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. This protein interacts with the proteinase inhibitor eglin c and is localized in the nucleus. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of PPIL2 Add / Edit PPIL2: Annotations

No community annotations yet for PPIL2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PPIL2 is highly significantly mutated in
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PPIL2 is significantly mutated in
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PPIL2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PPIL2