PPIL1 Back

peptidylprolyl isomerase (cyclophilin)-like 1

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NCBI Description of PPIL1
This gene is a member of the cyclophilin family of peptidylprolyl isomerases (PPIases). The cyclophilins are a highly conserved, ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. Based on similarity to other PPIases, this protein could accelerate the folding of proteins and might catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Community Annotation of PPIL1 Add / Edit PPIL1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PPIL1 is highly significantly mutated in
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PPIL1 is significantly mutated in
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PPIL1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PPIL1