peptidylprolyl isomerase D (cyclophilin D)

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NCBI Description of PPID

The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein has been shown to possess PPIase activity and, similar to other family members, can bind to the immunosuppressant cyclosporin A.

Community Annotation of PPID Add / Edit PPID: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PPID is highly significantly mutated in
PPID is significantly mutated in
PPID is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PPID