PTPRF interacting protein, binding protein 2 (liprin beta 2)

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NCBI Description of PPFIBP2

This gene encodes a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. The encoded protein is a beta liprin and plays a role in axon guidance and neuronal synapse development by recruiting LAR protein-tyrosine phosphatases to the plasma membrane. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of PPFIBP2 Add / Edit PPFIBP2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


PPFIBP2 is highly significantly mutated in
PPFIBP2 is significantly mutated in
PPFIBP2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for PPFIBP2