PPCDC Back

phosphopantothenoylcysteine decarboxylase

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NCBI Description of PPCDC
Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC (EC 4.1.1.36), one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine (Daugherty et al., 2002 [PubMed 11923312]).[supplied by OMIM, Mar 2008].

Community Annotation of PPCDC Add / Edit PPCDC: Annotations

No community annotations yet for PPCDC.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

PPCDC is highly significantly mutated in
(none)
PPCDC is significantly mutated in
(none)
PPCDC is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for PPCDC