POU5F1B Back

POU class 5 homeobox 1B

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NCBI Description of POU5F1B

This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional activator and may play a role in carcinogenesis and eye development.

Community Annotation of POU5F1B Add / Edit POU5F1B: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


POU5F1B is highly significantly mutated in
POU5F1B is significantly mutated in
POU5F1B is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for POU5F1B