POU4F2 Back

POU class 4 homeobox 2

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NCBI Description of POU4F2

The protein encoded by this gene is a member of the POU-domain transcription factor family and may be involved in maintaining visual system neurons in the retina. The level of the encoded protein is also elevated in a majority of breast cancers, resulting in accelerated tumor growth.

Community Annotation of POU4F2 Add / Edit POU4F2: Annotations

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Sort mutations by: Tumor type  Mutation type  Position  
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

POU4F2 is highly significantly mutated in
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POU4F2 is significantly mutated in
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POU4F2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for POU4F2