POU4F1 Back

POU class 4 homeobox 1

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NCBI Description of POU4F1
This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias.

Community Annotation of POU4F1 Add / Edit POU4F1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

POU4F1 is highly significantly mutated in
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POU4F1 is significantly mutated in
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POU4F1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for POU4F1