POU3F3 Back

POU class 3 homeobox 3

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NCBI Description of POU3F3

POU3F3 is a member of the class III POU family of transcription factors (see POU3F1; MIM 602479) that are expressed in the central nervous system. The POU domain in these proteins is required for high affinity binding to octamer DNA sequences (summarized by Sumiyama et al., 1996 [PubMed 8703082]).[supplied by OMIM, Jul 2010].

Community Annotation of POU3F3 Add / Edit POU3F3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

POU3F3 is highly significantly mutated in
(none)
POU3F3 is significantly mutated in
(none)
POU3F3 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for POU3F3