POU2F1 Back

POU class 2 homeobox 1

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NCBI Description of POU2F1

The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM, Jul 2010].

Community Annotation of POU2F1 Add / Edit POU2F1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


POU2F1 is highly significantly mutated in
POU2F1 is significantly mutated in
POU2F1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for POU2F1