NCBI Description of PON1
|The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.|
Community Annotation of PON1 Add / Edit PON1: Annotations
No community annotations yet for PON1.
Click on a tumor type to see its full list of significant genes.