POLRMT Back

polymerase (RNA) mitochondrial (DNA directed)

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NCBI Description of POLRMT
This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes.

Community Annotation of POLRMT Add / Edit POLRMT: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

POLRMT is highly significantly mutated in
(none)
POLRMT is significantly mutated in
(none)
POLRMT is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for POLRMT