polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa

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NCBI Description of POLR2K

This gene encodes one of the smallest subunits of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases.

Community Annotation of POLR2K Add / Edit POLR2K: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


POLR2K is highly significantly mutated in
POLR2K is significantly mutated in
POLR2K is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for POLR2K