POLR2J Back

polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa

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NCBI Description of POLR2J

This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene exists as a heterodimer with another polymerase subunit; together they form a core subassembly unit of the polymerase. Two similar genes are located nearby on chromosome 7q22.1 and a pseudogene is found on chromosome 7p13.

Community Annotation of POLR2J Add / Edit POLR2J: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

POLR2J is highly significantly mutated in
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POLR2J is significantly mutated in
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POLR2J is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for POLR2J