POLR2F Back

polymerase (RNA) II (DNA directed) polypeptide F

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of POLR2F

This gene encodes the sixth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes, that is also shared by the other two DNA-directed RNA polymerases. In yeast, this polymerase subunit, in combination with at least two other subunits, forms a structure that stabilizes the transcribing polymerase on the DNA template. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no quality transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.

Community Annotation of POLR2F Add / Edit POLR2F: Annotations

No community annotations yet for POLR2F.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

POLR2F is highly significantly mutated in
(none)
POLR2F is significantly mutated in
(none)
POLR2F is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for POLR2F