polymerase (RNA) II (DNA directed) polypeptide D

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NCBI Description of POLR2D

This gene encodes the fourth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, this polymerase subunit is associated with the polymerase under suboptimal growth conditions and may have a stress protective role. A sequence for a ribosomal pseudogene is contained within the 3' untranslated region of the transcript from this gene.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


POLR2D is highly significantly mutated in
POLR2D is significantly mutated in
POLR2D is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for POLR2D